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Articles
Published: 2023-10-09

Primary testicular lymphoma in undescended testis of a middle-age man: a case report

Urology consultant at king Abdulaziz hospital, Makkah, Saudi Arabia
Urology specialist at king Abdulaziz hospital, Makkah, Saudi Arabia
Radiology consultant at king Abdulaziz hospital, Makkah, Saudi Arabia
Anatomical pathology consultant at king Abdulaziz hospital, Makkah, Saudi Arabia

Abstract

Background: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extra-nodal non-Hodgkin lymphoma (NHL), accounting for <5.0% of testicular malignancies and 1.0% to 2.0% of NHL cases with a median age at diagnosis of 66 to 68 years. PTL accounts for 1–9% of testicular malignancies and 1–2% of NHLs. There are a handful of described lymphomas in the literature affecting normally positioned testis of aged men, yet none were reported in a cryptorchid middle-aged man. PTL is an extremely aggressive malignancy with poor progression-free survival and overall survival.

Case presentation: A 47-year-old man presented to the urology clinic complaining of multiple painless swellings in the neck and groins. He also complains of back pain, drenching night sweats, a swollen right lower limb, constipation, anorexia, weight loss, and occasional vomiting. The illness's duration is 2 months. He had a right inguinal testis. Histology examination of the excised testis and lymph nodes revealed an advanced “diffuse large beta-cell lymphoma” in both. The patient was referred for oncology care.

Conclusion: It is an extremely rare case of Diffuse Large B-Cell Lymphoma (DLBCL) in the undescended testis of a middle-aged man. To the best of our knowledge, this is the first published case of its kind about the tumor's type, testis anomaly, and patient's age.



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How to Cite

1.
Katib A, Dakkak B, Ahmad A, Mowalwei H. Primary testicular lymphoma in undescended testis of a middle-age man: a case report. jidhealth [Internet]. 2023 Oct. 9 [cited 2024 Jun. 20];6(3):955-8. Available from: https://jidhealth.com/index.php/jidhealth/article/view/310