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Published: 2020-10-01

The sequel to COVID-19: the antithesis to life

Department of Medicine, Sawai Man Singh Medical College and attached group of Hospitals, Jaipur, Rajasthan, India
Department of Medicine, Sawai Man Singh Medical College Hospital, Jaipur, Rajasthan, India
Department of Physiology, Government Medical College, Barmer, Rajasthan, India
Department of Physiology, Sawai Man Singh Medical College Hospital, Jaipur, Rajasthan, India
Department of Pharmacology, Sawai Man Singh Medical College Hospital, Jaipur, Rajasthan, India
Department of Physiology, S. M. S. Medical College and attached group of Hospitals, Jaipur, Rajasthan, India
Department of Physiology, Sawai Man Singh Medical College Hospital, Jaipur, Rajasthan, India
Department of Medicine, S. M. S. Medical College and attached group of Hospitals, Jaipur, Rajasthan, India
Psychosocial, Mental Health, COVID-19, Social Isolation, Quarantine, Infodemic, India


The pandemic of COVID-19 has afflicted every individual and has initiated a cascade of directly or indirectly involved events in precipitating mental health issues. The human species is a wanderer and hunter-gatherer by nature, and physical social distancing and nationwide lockdown have confined an individual to physical isolation. The present review article was conceived to address psychosocial and other issues and their aetiology related to the current pandemic of COVID-19. The elderly age group has most suffered the wrath of SARS-CoV-2, and social isolation as a preventive measure may further induce mental health issues. Animal model studies have demonstrated an inappropriate interacting endogenous neurotransmitter milieu of dopamine, serotonin, glutamate, and opioids, induced by social isolation that could probably lead to observable phenomena of deviant psychosocial behavior. Conflicting and manipulated information related to COVID-19 on social media has also been recognized as a global threat. Psychological stress during the current pandemic in frontline health care workers, migrant workers, children, and adolescents is also a serious concern. Mental health issues in the current situation could also be induced by being quarantined, uncertainty in business, jobs, economy, hampered academic activities, increased screen time on social media, and domestic violence incidences. The gravity of mental health issues associated with the pandemic of COVID-19 should be identified at the earliest. Mental health organization dedicated to current and future pandemics should be established along with Government policies addressing psychological issues to prevent and treat mental health issues need to be developed.



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Bhandari S, Shaktawat AS, Patel B, Dube A, Kakkar S, Tak A, Gupta J, Rankawat G. The sequel to COVID-19: the antithesis to life. jidhealth [Internet]. 2020 Oct. 1 [cited 2024 Jul. 23];3(Special1):205-12. Available from: